Selected publications
Szkopek D, Wychowański P, Zaworski K, Seklecka B, Starzyński R, Lipiński P, Pierzynowska K, Pierzynowski SG, Donaldson J, Paczewski Ł, Woliński J. Investigating the Influence of a Tooth Absence on Facial Bone Growth Using a Porcine Model. Int J Mol Sci. 2024 Nov 21;25(23):12509. doi: 10.3390/ijms252312509. PMID: 39684221; PMCID: PMC11640821.
Pierzynowska K, Zaworski K, Wychowański P, Donaldson J, Woliński J, Borowitz D, Gallotto R, Pierzynowski S. Modified throughput ninhydrin method for the qualitative assessment of dietary protein absorption in pig plasma. Biol Methods Protoc. 2024 Oct 25;9(1):bpae078. doi: 10.1093/biomethods/bpae078. PMID: 39512855; PMCID: PMC11543343.
Pierzynowska K., Wychowański P., Zaworski K., Woliński J., Donaldson J., Szkopek D., Roszkowicz-Ostrowska K., Kondej A., Pierzynowski S.G. Amylase intrapancreatic infusion delays insulin release during an intravenous glucose tolerance test, proof of acini–islet–acinar interactions.World J Exp Med2024;14(3): 92589 [DOI: 10.5493/wjem.v14.i3.92589]
Szkopek D., Pierzynowski S.G., Pierzynowska K., Zaworski K., Kondej A., Wychowański P., Konieczka P., Seklecka B., Donaldson J., Jank M., Woliński J. A review: Pancreatic enzymes in the treatment of chronic pancreatic insufficiency in companion animals.
J Vet Intern Med. 2024;1–8. https://doi.org/10.1111/jvim.17096
Cai W., Pierzynowska K., Stiernborg M., Xu J., Nilsson I.AK., Svensson U., Melas P.A., Catharina Lavebratt C. Multispecies synbiotics alleviate dextran sulfate sodium (DSS)-
induced colitis: Effects on clinical scores, intestinal pathology, and plasma biomarkers in male and female mice. Clin Nutr ESPEN;63: 74-83, 2024
Buddington KK, Pierzynowski SG, Holmes WE, Buddington RK. Selective and Concentrative Enteropancreatic Recirculation of Antibiotics by Pigs. Antibiotics. 2024; 13(1):12. https://doi.org/10.3390/antibiotics13010012
Pierzynowska K, Wychowański P, Zaworski K, Woliński J, Donaldson J, Pierzynowski S. Anti-Incretin Gut Features Induced by Feed Supplementation with Alpha-Amylase: Studies on EPI Pigs. Int J Mol Sci. 2023 Nov 10;24(22):16177. doi: 10.3390/ijms242216177. PMID: 38003366; PMCID: PMC10671445.
Dominika Szkopek1lek, Agata Kondej1mgr, Kamil Zaworski, Stefan Grzegorz Pierzynowski, Katarzyna Pierzynowska, Piotr Wychowański, Paweł Konieczka, Blanka Seklecka, Jarosław Woliński. Terapia zastępcza enzymami trzustkowymi w przebiegu przewlekłej niewydolności trzustki u psów i kotów. Magazyn Weterynaryjny | Monografia, 2023.
Stefan G Pierzynowski, Christine Stier, Kateryna Pierzynowska. Hypothesis that alpha-amylase evokes regulatory mechanisms originating in the pancreas, gut and circulation, which govern glucose/insulin homeostasis. World J Diabetes 2023;14(9): 1341-1348.
https://doi.org/10.4239/wjd.v14.i9.1341
M. Czauderna, M. Karpińska, J. Woliński, K. Zaworski, M. Białek, S. Pierzynowski, W. Wojtak., K. Pierzynowska. Improved lipid saponification for chromatographic quantification of fatty acids in porcine erythrocytes – an important lipidomic
biomarker of the effectiveness of dietary fat supplementation in pigs as a large animal model for human studies. Journal of Animal and Feed Sciences, 32, 4 2023, xxx–xxx https://doi.org/10.22358/jafs/163632/2023
Steven D. Freedman, Kamil Zaworski, Kateryna Pierzynowska, Stefan Pierzynowski, Robert Gallotto, Meghana Sathe, Drucy S. Borowitz. Validation of an omega-3 substrate challenge. PLoS ONE 18(5): e0284651. https://doi.org/10.1371/journal.pone.0284651
Monika Słupecka-Ziemilska, Stefan Grzegorz Pierzynowski, Paulina Szczurek, Kateryna Pierzynowska, Piotr Wychowanski , Blanka Seklecka, Maciej Koperski, Anna Starzynska, Dominika Szkopek, Janine Donaldson, Krzysztof Andrzejewsk and Jarosław Wolinski. Milk Formula Enriched with Sodium Butyrate Influences Small Intestine Contractility in Neonatal Pigs. Nutrients 2022, 14, 4301. https://doi.org/10.3390/nu14204301
Kateryna Pierzynowska, Sofia Thomasson, Stina Oredsson. Alpha-Amylase Inhibits Cell Proliferation and Glucose Uptake in Human Neuroblastoma Cell Lines. Hindawi BioMed Research International Volume 2022, Article ID 4271358, 11 pages https://doi.org/10.1155/2022/4271358
Björn Weström and Stefan G. Pierzynowski. Editorial: Precocious Gut Maturation: Environmental and Dietary Factors. Front. Nutr., 2022 Sec. Nutrition and Metabolism https://doi.org/10.3389/fnut.2022.868722
Kamil Zaworski, Jarosław Woliński, Monika Słupecka-Ziemilska, Stefan Pierzynowski, Kateryna Pierzynowska. Pre-digestion of the lipids in infant formula affects gut maturation of the preterm pig. PLOS ONE. https://doi.org/10.1371/journal.pone.0265144 March 16, 2022
Pierzynowski S.G., Pierzynowska K. Alpha-ketoglutarate, a key molecule involved in nitrogen circulation in both animals and plants, in the context of human gut microbiota and protein metabolism. Advances in Medical Sciences Volume 67, Issue 1, March 2022, Pages 142-147 https://doi.org/10.1016/j.advms.2022.02.004
Pierzynowski S.G., Socha-Banasiak A.,4 Sobol M., Skiba G., Raj S., Dovban O., Ushakova G., Woliński J., Mosiichuk N., Szczurek-Janicka P., Pieszka M., Kamyczek M., Święch E., Shmigel H., Sonta M., Czkwianianc E., Pierzynowska K. Difference in Performance of EPI Pigs Fed Either Lipase-Predigested or Creon®-Supplemented Semielemental Diet Volume 2021 |Article ID 6647734 | https://doi.org/10.1155/2021/6647734
Socha-Banasiak A., Pierzynowski S.G., Szczurek P., J Woliński J., A Wesołowska A., Czkwianianc E., Pierzynowska K. Gut response to pasteurized donor human milk in a porcine model of the premature infant // J Biol Regul Homeost Agents. 2020;34(6):2003-2015. doi: 10.23812/20-272-A.
Pierzynowska K., Oredsson S., Pierzynowski SG. Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRINBD11 // Journal of Diabetes Research. Volume 2020, Article ID 2148740, 10 pages https://doi.org/10.1155/2020/2148740
Pierzynowska K., Deshpande A., Mosiichuk N., Terkeltaub R., Szczurek P., Salido E., Pierzynowski S., Grujic D. Oral Treatment With an Engineered Uricase, ALLN-346, Reduces Hyperuricemia, and Uricosuria in Urate Oxidase-Deficient Mice // Front Med (Lausanne). 2020; 7: 569215. doi: 10.3389/fmed.2020.569215
Woliński J., Szczurek P., Pierzynowska K., Wychowański P., Seklecka B., Boryczka M., Kuwahara A., Kato I., Drahanchuk O., Zaworski K., Pierzynowski S.G., Słupecka-Ziemilska M. Influence of obestatin on the histological development of the small intestine in piglets during the first week of postnatal life // Animal (2020), 14:10, pp 2129–2137 doi:10.1017/S1751731120000919
Pierzynowska K, Woliński J, Weström B, Jazwiec R, Shmigel H, Pierzynowski SG. Absorption of Polyunsaturated Fatty Acid (PUFA) Is Related to IgG Blood Levels of Neonatal Pigs during the First 48 Hours Postpartum. J Immunol Res. 2020 Feb 6;2020:3813250. doi: 10.1155/2020/3813250.
Pierzynowska K, Woliński J, Weström B, Pierzynowski SG. Maternal Immunoglobulins in Infants-Are They More Than Just a Form of Passive Immunity? Front Immunol. 2020;11:855. doi: 10.3389/fimmu.2020.00855.
Weström B, Arévalo Sureda E, Pierzynowska K, Pierzynowski SG, Pérez-Cano FJ. The Immature Gut Barrier and Its Importance in Establishing Immunity in Newborn Mammals. Front Immunol. 2020;11:1153. doi: 10.3389/fimmu.2020.01153.
Woliński J, Szczurek P, Pierzynowska K, Wychowański P, Seklecka B, Boryczka M, Kuwahara A, Kato I, Drahanchuk O, Zaworski K, Pierzynowski SG, Słupecka-Ziemilska M. Influence of obestatin on the histological development of the small intestine in piglets during the first week of postnatal life. Animal. 2020;14(10):2129-2137. doi: 10.1017/S1751731120000919.
Pierzynowska K., Woliński J., 1 Weström B., Jazwiec R., 4 Shmigel H., and Pierzynowski S.G. Absorption of Polyunsaturated Fatty Acid (PUFA) Is Related to IgG Blood Levels of eonatal Pigs during the First 48 Hours Postpartum. Journal of Immunology Research Volume 2020, Article ID 3813250, 8 pages https://doi.org/10.1155/2020/3813250. Abstract or full-text
Mosiichuk N., Grujic D., J. Woliński J., Podpryatov S.E., Podpriatov S.S., Szczurek P.,
Yatsenko T., Shmihel H., Drahanchuk O., Pierzynowski S.G., Goncharova Pierzynowska K. Uricemia in juvenile pigs model: effect of nephrectomy and potassium oxonate. Journal of Animal and Feed Sciences. 2019; 28:254-262.
Pierzynowski SG, Gregory PC, Filip R, Woliński J, Pierzynowska KG. Glucose homeostasis dependency on acini-islet-acinar (AIA) axis communication: a new possible pathophysiological hypothesis regarding diabetes mellitus. Nutr Diabetes. 2018;8(1):55. doi: 10.1038/s41387-018-0062-9.
Pierzynowska KG, Lozinska L, Woliński J, Pierzynowski S. The inverse relationship between blood amylase and insulin levels in pigs during development, bariatric surgery, and intravenous infusion of amylase. PLoS One. 2018;13(6):e0198672. doi: 10.1371/journal.pone.0198672. eCollection 2018.
Pierzynowska K, Valverde-Piedra J, Szymanczyk S, Prykhod'ko O, Pieszka M, Kardas M, Grochowska-Niedworok E, Grabowski T, Winiarczyk M, Pierzynowski S. Pancreatic-like enzymes of microbial origin restore growth and normalize lipid absorption in a pig model with exocrine pancreatic insufficiency. Arch Med Sci. 2018;14(2):407-414. doi: 10.5114/aoms.2018.73471.
Szczurek P, Mosiichuk N, Woliński J, Yatsenko T, Grujic D, Lozinska L, Pieszka M, Święch E, Pierzynowski SG, Goncharova K. Oral uricase eliminates blood uric acid in the hyperuricemic pig model. PLoS One. 2017;12(6):e0179195. doi: 10.1371/journal.pone.0179195. eCollection 2017.
Pierzynowski SG, Goncharova K, Gregory PC, Weström B, Podpryatov SE, Podpriatov SS, Woliński J, Repich H, Wierup N, Lozinska L. Experiments suggesting extra-digestive effects of enteral pancreatic amylase and its peptides on glucose homeostasis in a pig model. Sci Rep. 2017;7(1):8628. doi: 10.1038/s41598-017-07387-2
Goncharova K, Lozinska L, Arevalo Sureda E, Woliński J, Weström B, Pierzynowski S. Importance of neonatal immunoglobulin transfer for hippocampal development and behaviour in the newborn pig. PLoS One. 2017 Jun 28;12(6):e0180002. doi: 10.1371/journal.pone.0180002. eCollection 2017.
Socha-Banasiak A, Pierzynowski S, Woliński J, Grujic D, Boryczka M, Grzesiak P, Szczurek P, Czkwianianc E, Westrom B, Goncharova K. The pig as a model for premature infants - the importance of immunoglobulin supplementation for growth and development. J Biol Regul Homeost Agents. 2017;31(1):87-92.
Dobrowolski P, Tomaszewska E, Muszyński S, Blicharski T, Pierzynowski SG. Dietary 2-oxoglutarate prevents bone loss caused by neonatal treatment with maximal dexamethasone dose. Exp Biol Med (Maywood). 2017;242(7):671-682. doi: 10.1177/1535370217693322.
Arévalo Sureda E, Weström B, Pierzynowski SG, Prykhodko O. Correction: Maturation of the Intestinal Epithelial Barrier in Neonatal Rats Coincides with Decreased FcRn Expression, Replacement of Vacuolated Enterocytes and Changed Blimp-1 Expression. PLoS One. 2017;12(1):e0169724. doi: 10.1371/journal.pone.0169724.
Lindqvist A, Ekelund M, Garcia-Vaz E, Ståhlman M, Pierzynowski S, Gomez MF, Rehfeld JF, Groop L, Hedenbro J, Wierup N1, Spégel P.The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model. PLoS One. 2017;12(3):e0173137. doi: 10.1371/journal.pone.0173137.
Lindqvist A, Ekelund M, Pierzynowski S, Groop L, Hedenbro J, Wierup N. Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels. Peptides. 2017 Apr;90:78-82. doi: 10.1016/j.peptides.2017.02.009.